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Molecular architecture and function of ZnT transporters
The ZnT transporters function as Zn (2+)/H (+) exchangers. Based on the X-ray structures of and sequence homology to bacterial homologues, they are thought to form dimers possessing one essential zinc-binding site within the transmembrane domains of each monomer, and a binuclear zinc-sensing and binding site in the cytoplasmic C-terminal …
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